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Source: http://news.idr-inc.com/2012/12/happy-holidays/
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Thursday, December 27, 2012
Snowstorm heads east after South twisters; 3 dead
MOBILE, Ala. (AP) ? An enormous storm system that dumped snow and sleet on the nation's midsection and unleashed damaging tornadoes around the Deep South began punching its way toward the Northeast on Wednesday, slowing holiday travel.
Post-Christmas travelers braced for flight delays and a raft of weather warnings for drivers, a day after rare winter twisters damaged buildings in Louisiana and Alabama.
Snow and ice covered roads in southern Illinois and southern Indiana early Wednesday. Officials urged residents to stay home if they can. State police reported numerous slide-off accidents in the Evansville, Ind., area and white-out conditions on Interstate 64 in Indiana with wind gusts around 30 mph.
The storm system headed from the Gulf Coast to New England has been blamed for three deaths and several injuries, though no one was killed outright in the tornadoes. In snowy Arkansas, the storm left more than 189,000 customers without electricity Wednesday, utility Entergy Arkansas said.
Severe thunderstorms were forecast for the Carolinas while a line of blizzard and winter storm warnings stretched from Arkansas up the Ohio River to New York and on to Maine.
Thirty-four tornadoes were reported in Texas, Louisiana, Mississippi and Alabama during the outbreak Tuesday, the National Weather Service said.
Rick Cauley's family was hosting relatives for Christmas when tornado sirens went off in Mobile. Not taking any chances, he and his wife, Ashley, hustled everyone down the block to take shelter at the athletic field house at Mobile's Murphy High School in Mobile.
It turns out, that wasn't the place to head.
"As luck would have it, that's where the tornado hit," Cauley said. "The pressure dropped and the ears started popping and it got crazy for a second." They were all fine, though the school was damaged, as were a church and several homes, but officials say no one was seriously injured.
Camera footage captured the approach of the large funnel cloud.
Mobile was the biggest city hit by numerous twisters. Along with brutal, straight-line winds, the storms knocked down countless trees, blew the roofs off homes and left many Christmas celebrations in the dark. Torrential rains drenched the region and several places saw flash flooding.
More than 325 flights around the U.S. were canceled as of Wednesday morning, according to the flight tracker FlightAware.com. The cancelations were mostly spread around airports that had been or soon would be in the path of the storm.
Holiday travelers in the nation's much colder midsection battled treacherous driving conditions from freezing rain and blizzard conditions from the same fast-moving storms. In Arkansas, highway department officials said the state was fortunate the snowstorm hit on Christmas Day when many travelers were already at their destinations.
Texas, meanwhile, dealt with high winds and slickened highways.
On Tuesday, winds toppled a tree onto a pickup truck in the Houston area, killing the driver, and a 53-year-old north Louisiana man was killed when a tree fell on his house. Icy roads already were blamed for a 21-vehicle pileup in Oklahoma, and the Highway Patrol there says a 28-year-old woman was killed in a crash on a snowy U.S. Highway near Fairview.
Trees fell on homes and across roadways in several communities in southern Mississippi and Louisiana. Mississippi Gov. Phil Bryant declared a state of emergency, saying eight counties reported damages and some injuries.
It included McNeill, where a likely tornado damaged a dozen homes and sent eight people to the hospital, none with life-threatening injuries, said Pearl River County emergency management agency director Danny Manley.
The snowstorm that caused numerous accidents pushed out of Oklahoma late Tuesday, carrying with it blizzard warnings for parts of northeast Arkansas, where 10 inches of snow was forecast. Freezing rain clung to trees and utility lines in Arkansas and winds gusts up to 30 mph whipped them around, causing about 71,000 customers to lose electricity for a time.
Christmas lights also were knocked out with more than 100,000 customers without power for at least a time in Texas, Arkansas, Oklahoma, Mississippi, Louisiana and Alabama.
Blizzard conditions were possible for parts of Illinois, Indiana and Kentucky up to Cleveland with predictions of several inches to a foot of snow. By the end of the week, that snow was expected to move into the Northeast with again up to a foot predicted
Jason Gerth said the Mobile tornado passed by in a few moments and from his porch, he saw about a half-dozen green flashes in the distance as transformers blew. His home was spared.
"It missed us by 100 feet and we have no damage," Gerth said.
In Louisiana, quarter-sized hail was reported early Tuesday in the western part of the state and a WDSU viewer sent a photo to the TV station of what appeared to be a waterspout around the Lake Pontchartrain Causeway in New Orleans. There were no reports of crashes or damage.
Some mountainous areas of Arkansas' Ozark Mountains could get up to 10 inches of snow, which would make travel "very hazardous or impossible" in the northern tier of the state from near whiteout conditions, the weather service said.
The holiday may conjure visions of snow and ice, but twisters this time of year are not unheard of. Ten storm systems in the last 50 years have spawned at least one Christmastime tornado with winds of 113 mph or more in the South, said Chris Vaccaro, a National Weather Service spokesman in Washington, via email.
The most lethal were the storms of Dec. 24-26, 1982, when 29 tornadoes in Oklahoma, Missouri, Arkansas, Tennessee and Mississippi killed three people and injured 32.
In Mobile, a large section of the roof on the Trinity Episcopal Church is missing and the front wall of the parish wall is gone, said Scott Rye, a senior warden at the church in the Midtown section of the city.
On Christmas Eve, the church with about 500 members was crowded for services.
"Thank God this didn't happen last night," Rye said.
___
Associated Press writers Jay Reeves in Birmingham, Ala., Jeff Amy in Atlanta, Ramit Plushnick-Masti in Houston, Chuck Bartels in Little Rock, Ark., Janet McConnaughey in New Orleans and AP Business Writer Daniel Wagner in Washington, contributed to this report.
Source: http://news.yahoo.com/snowstorm-heads-east-south-twisters-3-dead-092714438--finance.html
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Monday, December 24, 2012
Ne-Yo's Ex-Baby Mama Threatens Legal Action ... You Blabbed ...
Ne-Yo's Ex-Baby Mama
Threatens Legal Action ...
You Blabbed, Time to Pay!
EXCLUSIVE
Ne-Yo's former baby mama (we'll explain) is FUMING after the singer went on VH1 and blabbed about their baby drama -- and now she's hired mega attorney Gloria Allred to make him pay. It's a pretty complicated story ... Ne-Yo used to have a relationship with a woman named Jesseca White. During their time together, Jesseca had a baby which Ne-Yo thought was his ... turns out, it wasn't.
The couple reached a settlement agreement in 2009 in which Ne-Yo coughed up $575,000 to Jesseca, who in turn officially said the kid wasn't his. Ne-Yo was originally listed on the birth certificate as the father, but his name was later removed.
As part of the deal, both sides agreed to a confidentiality clause, promising to never go public with the info.?Fast forward to September 2012 ... Ne-Yo did an interview with VH1's "Behind the Music" and spilled the beans on the whole sordid ordeal.
Now, Gloria Allred has fired off a letter to Ne-Yo accusing him of breaking the agreement. Allred claims that because Ne-Yo falsely painted Jesseca as a harlot who lied, broke his heart and then vanished ...?Jesseca has been defamed, ridiculed and harassed.
According to the letter, Jesseca has been unable to work, was forced to file for state aid, suffers from mental anguish and is "beset by nausea, vomiting and hair loss" thanks to Ne-Yo's remarks.
Jesseca is asking Ne-Yo to settle the matter amicably out of court (cough, cough $$$$) ... otherwise she'll be forced to pursue more serious legal options.
We reached out to Ne-Yo's rep -- so far, no word back.
Source: http://www.tmz.com/2012/12/23/ne-yo-baby-mama-gloria-allred-letter/
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YouTube Took 2 Billion Views Away from Sony, Universal, and Others
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December 22, 1938: "Old Four Legs"
One of the most astounding scientific discoveries of the 20th century was initiated by a simple phone call, early in the morning of December 22, 1938. ?Miss Latimer, we got here one and a half ton of fish, maybe you are interested??
Marjorie Courtaney-Latimer, curator of the little museum of East London (South Africa), went to the harbour as many times before, to inspect the catch of the local fishermen for new specimens for the museum. At a first glimpse nothing special, but then ?There was the most marvellous fish I have ever seen. Dark blue, metallic, with white spots and a strange iridescence. It was 1,5 meter long.? ?A strange fish, Miss, for over thirty years I?m fishing in this region, but such one I have never seen.?
Latimer recognized the fish as something special. Consulting some books see recognized similarities to the reconstruction of fossil fish species, thought to be extinct at least since the demise of the dinosaurs, 65 million years ago. Latimer contacted the only available expert in South Africa ? James L.B. Smith of the Rhodes University in Grahamstown. From a drawing send to him by Latimer also Smith recognized the captured fish as member of the order Coelacanthiformes, or Coelacanths. Smith will describe the new fish species as Latimeria chalumnae, in honour of Courtenary-Latimer and after the estuary of the river Chalumna, where the animal was captured.
Source: http://rss.sciam.com/click.phdo?i=4852a0a8eb930376167ae54304d34b7e
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Sunday, December 23, 2012
Research sheds new light on mechanisms of T-ALL, a form of leukemia that primarily affects children
Dec. 23, 2012 ? Acute lymphatic leukemia (ALL) is the most common cancer in children under the age of 14 years. With optimum treatment, approximately 75 percent of children are currently cured, but the treatment consists of severe chemotherapy with many side effects. In collaboration with international research teams, scientists at VIB, KU Leuven and UZ Leuven have identified new genetic mutations that lead to T-ALL, a variant of ALL. They have unmasked the ribosome -- the molecular machine in the cell that is involved in the production of proteins -- as a weak spot in leukemia cells.
Their research has also shown that there is a difference in T-ALL between adults and children. Both findings can be important in the search for improved treatments for T-ALL.
Jan Cools (VIB/KU Leuven): "We have discovered that there is a clear genetic difference between T-ALL in children and in adults. This could be an explanation why adults do not respond as well to the current therapy."
Stein Aerts (KU Leuven): "This is a beautiful example of the power of genome sequencing in cancer research. New technologies and large-scale bio-informatics allow us to study a lot of data simultaneously. This allows us to discover links that would have been impossible to find in the past."
T-cell acute lymphatic leukemia (T-ALL)
The formation of white blood cells is disrupted by leukemia. The cells in the bone marrow that should mature into white blood cells multiply unchecked without maturing completely. These immature blood cells compromise the production of normal blood cells. This makes patients more susceptible to infections. Leukemia occurs in different forms; in the case of T-ALL, there is an accumulation of immature white blood cells over a very short period of time. With optimum treatment -- involving chemotherapy -- approximately 75 % of children are currently cured. For adults, the chance of a cure is below 50 %. Chemotherapy is associated with many side effects. The search for a more specific treatment can only start once we know what causes T-ALL.
7 new genes with a key role in T-ALL identified
T-ALL only occurs if errors in various genes occur simultaneously. It is important to determine which genes play a key role. Kim De Keersmaecker, Zeynep Kalender Atak, Jan Cools and Stein Aerts have identified a series of defects in 15 important genes, of which 7 have not previously been associated with T-ALL. They used next-generation sequencing to analyze the 20,000+ genes of 67 T-ALL patients. This technique allows for very fast analysis and comparison of the complete DNA sequence of healthy and sick individuals.
A difference between adults and children
The investigators from Leuven also discovered a difference between T-ALL in children and in adults. T-ALL in adults contains significantly more mutations than in children. The leukemia cells in adults also contain mutations in other genes than in children. This genetic difference could be a possible explanation why adults do not respond as well to the current therapy.
A weak point in leukemia cells exposed
RPL5 and RPL10 -- two newly identified genes -- form part of the ribosome: this is the complex in the cell that produces proteins. The scientists hereby demonstrated for the first time that defects in the ribosome can also play a role in cancer activation. Experiments in yeast cells confirm that mutations in RPL10 cause a change in the ribosome.
Kim De Keersmaecker (VIB/KU Leuven): "This could be a weak point of the leukemia cells: all cells need properly functioning ribosomes to survive and to grow. These 'defective' ribosomes in the leukemia cells could be a new suitable target for the development of targeted therapies."
Patient information
As this study may raise many questions in patients, we would like to refer you to the e-mail address that the VIB has set up for this purpose. Anyone with questions about this research and other medical research can submit their questions on patients@vib.be. Please submit your question in Dutch or English only.
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Story Source:
The above story is reprinted from materials provided by VIB, via AlphaGalileo.
Note: Materials may be edited for content and length. For further information, please contact the source cited above.
Journal Reference:
- Kim De Keersmaecker, Zeynep Kalender Atak, Ning Li, Carmen Vicente, Stephanie Patchett, Tiziana Girardi, Valentina Gianfelici, Ellen Geerdens, Emmanuelle Clappier, Micha?l Porcu, Idoya Lahortiga, Rossella Luc?, Jiekun Yan, Gert Hulselmans, Hilde Vranckx, Roel Vandepoel, Bram Sweron, Kris Jacobs, Nicole Mentens, Iwona Wlodarska, Barbara Cauwelier, Jacqueline Cloos, Jean Soulier, Anne Uyttebroeck, Claudia Bagni, Bassem A Hassan, Peter Vandenberghe, Arlen W Johnson, Stein Aerts, Jan Cools. Exome sequencing identifies mutation in CNOT3 and ribosomal genes RPL5 and RPL10 in T-cell acute lymphoblastic leukemia. Nature Genetics, 2012; DOI: 10.1038/ng.2508
Note: If no author is given, the source is cited instead.
Disclaimer: This article is not intended to provide medical advice, diagnosis or treatment. Views expressed here do not necessarily reflect those of ScienceDaily or its staff.
Source: http://feeds.sciencedaily.com/~r/sciencedaily/top_news/~3/t1aTr52MtSw/121223152437.htm
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